Sirolimus use and cancer incidence in US kidney transplant recipients
Recently we added to the Library as well as a blog a very good individual patient meta-analysis of the use of sirolimus showing that it was associated with a reduction in cancer incidence but also with an increased rate of death after kidney transplantation. Now we have a study of data from the US transplant registry […]
Read moreSirolimus and secondary skin cancer prevention in kidney transplantation
Sylvie Euvrard and her colleagues (New England Journal of Medicine 2012; 367:329) have performed a multicentre randomised trial in patients on a calcineurin inhibitor who had developed at least 1 squamous cell cancer of the skin after renal transplantation. Patients were randomised to either continue on the calcineurin inhibitor or to be converted to sirolimus. […]
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