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15th August 2016 / Last updated : 15th August 2016 Simon Knight Clinical trials

August 2016 Transplant Trial Watch now available

The August 2016 edition of the Transplant Trial Watch is now available. This month’s edition includes systematic reviews of pre-emptive renal transplantation and management of ureteric strictures, along with trials of prostaglandin E1 in liver transplant recipients and C1 esterase inhibition in renal transplantation.

1st July 2016 / Last updated : 1st July 2016 Simon Knight Clinical trials

July 2016 Transplant Trial Watch now available

The July 2016 edition of the Transplant Trial Watch is now available. This month, trials include long-term outcomes from BENEFIT-EXT, treatment of asymptomatic bacteriuria in renal transplant recipients and and in depth analysis of the VICTOR trial.

3rd June 2016 / Last updated : 3rd June 2016 Simon Knight Clinical trials

June 2016 Transplant Trial Watch is now online

The June 2016 Transplant Trial Watch is now available. This month, the trial watch includes systematic reviews of quality of life reporting in renal transplant trials and extended criteria donors, as well as an analysis of wound complications with everolimus following cardiac transplantation.

6th January 2016 / Last updated : 6th January 2016 Simon Knight Clinical trials

January 2016 Transplant Trial Watch now available

The CET team would like to wish everyone a Happy New Year! A new year means that this month’s Transplant Trial Watch is now out. New studies include a systematic review of outcomes in obese kidney transplant recipients, CNI and steroid-free immunosuppression in renal transplantation, and a direct mail campaign to improve donor registration.

5th November 2015 / Last updated : 5th November 2015 Liset Pengel Publications

Join the discussion: recipient obesity and outcome after renal transplantation

Two recent systematic reviews were published on this important topic. The review by Lafranca and colleagues entitled “Body mass index and outcome in renal transplant recipients: a systematic review and meta-analysis”(BMC Medicine 2015;13(1):111) included 56 studies. The authors concluded that “Several of the pooled outcome measurements show significant benefits for ‘low’ BMI (30 preferably should […]

6th January 2015 / Last updated : 6th January 2015 Peter Morris Reviews

Sirolimus associated with less malignancy but an increased mortality after kidney transplantation

A group from Ottawa, led by Greg Knoll, have published an important systematic review of risk of cancer in patients who had sirolimus included with their immunosuppression de novo as well as those who were converted at some stage after transplantation to sirolimus. The study also included a meta-analysis of individual patient data. This was […]

5th August 2014 / Last updated : 5th August 2014 Simon Knight Meta-analysis in R

Meta-analysis in R: Part 2 – Binary data

In part 1, I discussed how to get set up for meta-analysis in R, by installing the necessary software and libraries. In this post, I will take the reader through the steps for performing meta-analysis of binary data in R.

18th July 2014 / Last updated : 18th July 2014 Simon Knight Meta-analysis in R

Meta-analysis in R: Part 1 – Installing the software

When I am teaching about meta-analysis on the EVIT course, I often moan about the inflexibility of Cochrane’s Revman software and am asked what I use to perform my meta-analyses. My pechant for open-source software led me to use the R statistical environment. In this series of blog posts, that I will update over the […]

2nd May 2014 / Last updated : 2nd May 2014 Simon Knight Clinical trials

Transplant Trial Watch May 2014

The May 2014 edition of the transplant trial watch is now available on the CET site, as well as our mobile apps for iPhone, iPad and Android. This month, studies include a systematic review of hypothermic machine preservation in renal transplantation, metallic stents for biliary strictures following liver transplantation and tablet computer-based patient education.

21st February 2014 / Last updated : 21st February 2014 Peter Morris Journals

Origins of Evidence Based Medicine

There was an interesting editorial by Richard Smith and Drummond RennieĀ in the BMJ recently. The editorial is based on two interviews of pioneers in this field by Richard Smith, the former editor of the BMJ. In the first oral history he interviews Iain Chalmers, Muir Gray and David Sackett. They said that authors from a […]

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New Transplant Evidence App released!

21st December 2020

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