Long-term follow up of tracheal transplant
Recently there was note of a 5 year follow-up of the young woman, Claudia Castillio, who had a tissue engineered tracheal transplant in 2008. She has retained good lung function with no immunological complications and the only problem has been scarring around areas of the graft, particularly at the anastomoses which has required repeated endoluminal […]
Read moreBoston researchers create bioengineered kidney
Researchers in Boston, Massachusetts have published the first description of successful transplantation of a bioengineered kidney into rats. The paper, published in this week’s Nature Medicine describes the process of decellularization by detergent perfusion and regeneration with epithelial and endothelial cells. The resulting kidney was capable of filtering and producing urine both in vitro and […]
Read moreA tissue engineered vein graft – proof of concept
There was a very interesting report in the Lancet this past week from the Sahlgrenska University Hospital in Gothenburg in Sweden by Michael Olausson and colleagues describing the successful treatment of a ten year old girl with an extrahepatic portal vein obstruction. A 9cm length of an iliac vein from a deceased organ donor was […]
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