To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
March 2025
Kidney transplantation
Donor-derived cell-free DNA monitoring for early diagnosis of antibody-mediated rejection after kidney transplantation: a randomized trial.
Akifova, A., et al. Nephrology Dialysis Transplantation 2024 [record in progress].
A Five-Year Prospective, Randomized, Open-Label Study of Standard-Dose Versus Low-Dose Prolonged-Release Tacrolimus With or Without Angiotensin-Converting Enzyme Inhibitor or Angiotensin II Receptor Blocker Post Kidney Transplantation.
Campbell, P. M., et al. Clinical Transplantation 2025; 39(1): e70067
Review of plasma exchange and rituximab for prevention of recurrent focal segmental glomerulosclerosis after a prior graft loss.
Gharaei, S., et al. World Journal of Transplantation 2024; 14(4): 98155.
Adenovirus nephritis in adult kidney allograft recipients: a systematic review of literature.
Kiran, P. V. S., et al. Infection 2025 [record in progress]
The effect of the use of omeprazole versus famotidine on the kidney transplant function: a randomized controlled study.
Miedziaszczyk, M., et al. Scientific Reports 2025; 15(1): 1805.
Liver transplantation
N-Acetylcysteine and Liver Transplant. Advantages of its Administration in Multi-Organ Donors Especially During World-Economical-Crisis. Long-Term Sub-Group Analysis in a Randomized Study.
Finotti, M., et al. Transplantation Proceedings 2025 [record in progress].
Sarcopenic obesity is significantly associated with poorer overall survival after liver transplantation: a systematic review and meta-analysis.
Huang, H. B., et al. Frontiers in Nutrition 2024; 11: 1387602.
Randomized trial investigating the utility of a liver tissue transcriptional biomarker in identifying adult liver transplant recipients not requiring maintenance immunosuppression.
Vionnet, J., et al. American Journal of Transplantation 2024 [record in progress].
Heart transplantation
Is There an Association Between Living in a Rural Area and the Incidence of Postoperative Complications or Hospital Readmissions Following Left Ventricular Assist Device (LVAD) Implantation, Compared to Urban Lvad Recipients? A Systematic Review.
Gollapudi, S., et al. Clinical Cardiology 2025; 48(1): e70068.