Impact of Early Ureteric Stent Removal and Cost-benefit Analysis in Kidney Transplant Recipients: Results of a Randomized Controlled Study.
Parapiboon W, Ingsathit A, et al.Transplantation Proceedings, 44(3): 737-739, 2012.
Aims
To identify the incidence of and causative organism for bacteriuria in kidney transplant patients who were randomised to have a stent removed either early at 8 days after transplantation or later at 15 days.
Interventions
Removal of a ureteric stent at 8 days versus removal at 15 days after transplantation. All patients received intravenous cefuroxime, sulfamethoxazole/trimethoprim antibiotic prophylaxis. Immunosuppression included cyclosporine or tacrolimus, mycophenolate mofetil or myfortic and steroids.
Participants
74 renal transplant patients who received a living or deceased kidney.
Outcomes
Incidence of urinary tract infection (UTI) as well as identification of the organism. UTI was classified into symptomatic, asymptomatic and urosepsis.
Follow-up
1 month post-transplantation.
CET Conclusions
In this further analysis of the trial where patients were randomised to have a stent removed either early at 8 days after transplantation or later at 15 days, there was a much higher incidence of urinary tract infection in the patients with stents left in for 15 days. The most common organism identified was e-coli followed by klebsiella pneumoniae.
Data analysis
Per protocol analysis
Trial registration
Not reported