To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
February 2025
Kidney transplantation
Valacyclovir versus valganciclovir for cytomegalovirus prophylaxis in kidney transplant recipients: a systematic review and comparative meta-analysis.
Cardoso, L. J. C., et al. Clinical Transplantation and Research 2024 [record in progress].
A systematic review and meta-analysis of factors contributing to post-kidney transplant anemia and the effect of erythropoietin-stimulating agents.
Chienwichai, K., et al. Systematic Reviews 2024; 13(1): 278.
Effects of two immunosuppression regimens on T-lymphocyte subsets in elderly kidney transplant recipients.
Freitas, G. R. R., et al. Frontiers in Immunology 2024; 15: 1405855.
Serum and urine nucleic acid screening tests for BK polyomavirus-associated nephropathy in kidney and kidney-pancreas transplant recipients.
Maung Myint, T., et al. Cochrane Database of Systematic Reviews 2024; 11: CD014839.
Randomized Controlled Trial to Evaluate a New Tool to Support Patient Decision-making on Transplant Centers.
McKinney, W. T., et al. Clinical Transplantation 2024; 38(12): e70043.
Kidney Transplantation From Donors With Malignant Renal Masses: A Systematic Review.
Villani, V., et al. Clinical Transplantation 2024; 38(11): e70020.
Liver transplantation
Multicenter Randomised Controlled Trial of Single versus Double Venous Outflow Reconstruction in Right lobe Living Donor Liver Transplantation- Venous Outflow in Liver Transplantation (VOLT) Trial.
Reddy, M. S., et al. Annals of Surgery 2024 [record in progress].
Heart transplantation
The Effect of Everolimus Versus Calcineurin Inhibitors on Quality of Life 10-12 Years After Heart Transplantation: The Results of a Randomized Controlled Trial (SCHEDULE Trial).
Grov, I., et al. Clinical Transplantation 2024; 38(11): e70028.
Lung transplantation
Extracorporeal Photopheresis for the prevention of rejection after lung transplantation - a prospective randomized controlled trial.
Benazzo, A., et al. European Respiratory Journal 2024 [record in progress].
Various organs
Maribavir for refractory cytomegalovirus infection (with or without resistance) in solid organ transplant recipients: subgroup analysis of the phase 3 randomized SOLSTICE study.
Blumberg, E. A., et al. Journal of Heart & Lung Transplantation 2024 [record in progress].