High Incidence of Bacteriuria in Early Post-kidney Transplantation; Results from a Randomized Controlled Study.
Parapiboon W, Ingsathit A, et al.Transplantation Proceedings, 44(3): 734-736, 2012.
Aims
To compare the benefit and harm of early ureteric stent removal with routine removal in kidney transplant recipients.
Interventions
Removal of a ureteric stent at 8 days versus removal at 15 days after transplantation. All patients received intravenous cefuroxime, sulfamethoxazole/trimethoprim antibiotic prophylaxis. Immunosuppression included cyclosporine or tacrolimus, mycophenolate mofetil or myfortic and steroids.
Participants
74 renal transplant patients who received a living or deceased kidney.
Outcomes
Incidence of urinary tract infection (UTI) and urologic complications, as well as hospital cost for UTI and urologic complications.
Follow-up
1 to 2 months post-transplantation
CET Conclusions
The original trial was evaluating the removal of a ureteric stent at 8 days after transplantation in comparison with removal at 15 days which was their normal practice. The data suggests that early removal of the stent reduced the incidence of urinary tract infection and therefore hospitalisation. This was reflected in considerable savings in the early management of kidney transplant patients.
Data analysis
Per protocol analysis
Quality notes
This is a post hoc analysis of a previous publication of the same RCT: Parapiboon W, Ingsathit A, et al. "Impact of Early Ureteric Stent Removal and Cost-benefit Analysis in Kidney Transplant Recipients: Results of A Randomized Controlled Study." Transplantation Proceedings, 44(3): 737-739, 2012. The methodological quality assessment was based on the previous publication.
Trial registration
Not reported