Adenovirus nephritis in adult kidney allograft recipients: a systematic review of literature.
Kiran, P. V. S., et al.Infection 2025 [record in progress]
Aims
This study aimed to explain the clinical profile, diagnostic modalities, clinical outcomes and treatment strategies for adenoviral nephritis in kidney transplant recipients.
Interventions
Three main databases including PubMed, Embase and Web of Science were searched. Study selection and data extraction were conducted by two reviewers. Risk of bias was assessed using the Joanna Briggs Institute (JBI) critical appraisal tools for case reports.
Participants
39 studies were included in the review.
Outcomes
Clinical profile, biopsy findings, treatment strategies and treatment outcomes of adenoviral nephritis.
Follow-up
N/A
CET Conclusions
This systematic review summarises the literature regarding adenovirus nephritis following renal transplantation. The authors identify 39 articles with 57 patients and provide a narrative summary of the clinical presentation and outcomes. Overall, the review methodology is good, with prospective protocol registration, risk of bias assessment and multiple databases searched. The review is limited by the nature and quantity of published evident, but nonetheless provides a good, balanced summary of the available literature on the topic.
Trial registration
PROSPERO - CRD42024597199