Sequential versus Contemporaneous Portal and Arterial Reperfusion during Liver Transplantation.

Transplantation Proceedings. 43(4): 1107-110, 2011.

Aims
To compare the outcome of sequential portal and arterial reperfusion with the simultaneous revascularisation of the portal vein and hepatic artery in liver transplant patients.

Interventions
Revascularisation of a liver transplant by sequential portal and then arterial revascularisation versus simultaneous revascularisation of the portal vein and hepatic artery during liver transplantation.

Participants
40 liver transplant patients from heart-beating donors.

Outcomes
One-year graft and patient survival, and biliary complications including anastomotic stenosis and intrahepatic nonanastomotic biliary strictures. Incidence of hepatocellular carcinoma, hepatitis C, macrovacuolar steatosis, delayed graft function, duration of liver transplantation, cold ischemia times, warm ischemia time, intensive care unit and total hospital stay, and level of aspartate aminotransferase, alanine aminotransferase and total bilirubin.

Follow-up
12 months

CET Conclusions
CET’s conclusions: There was no difference in most outcomes with the two techniques except that intrahepatic non anastomotic biliary strictures occurred in 26% of the patients who had a sequential revascularisation compared to none in the patients having a simultaneous portal and arterial revascularisation.

Jadad score
1

Data analysis
Per protocol analysis

Allocation concealment
No

Trial registration
Not reported

Funding source
Not reported