Transplant Trial Watch

Predictors and Moderators of Educational Interventions to Increase the Likelihood of Potential Living Donors for Black Patients Awaiting Kidney Transplantation.

Rodrigue JR, Paek MJ, et al.

J Racial Ethn Health Disparities 2016 [record in progress].


Aims
To identify predictors and moderators of the effects of three educational conditions on the likelihood of black kidney transplant candidates to have living donor (LD) evaluations initiated, and live donor kidney transplantation (LDKT).

Interventions
Participants were randomised to receive one of three health educator led 60-to 90-minute educational sessions comprising culturally relevant content focused on LDKT and living donation and supplemented with video and print materials. These were either delivered to the patient and his/her invited guests in the patient’s home (HC group), versus a group-based session where education was delivered to groups of patients and their invited guests in the transplant centre (GB group), versus an individual counselling session where education was delivered to the patient alone in the transplant centre

Participants
152 adult, black race kidney transplant candidates eligible for kidney transplantation, aged ≥21 years old living within two and a half-hour drive of a northeastern USA medical center.

Outcomes
The primary outcome measured was the likelihood of LDKT occurrence. The secondary measured outcome was LD evaluation occurrence.

Follow-up
2 years

CET Conclusions
Black adults waitlisted for kidney transplantation were randomised to a house call educational session, group-based session or individual counselling session aimed to increase the likelihood of live donor kidney transplantation. The primary analysis of the trial was reported separately and this exploratory analysis focused on predictors and moderators of initiating a living donor evaluation. Significant predictors in the multivariate model were house call assignment, younger age, more willingness to discuss living donation with others and a larger social network. Factors that moderated the effects of house calls were age and social network size. The outcomes of this explorative analysis may be used for further research on this topic.

Jadad score
3

Data analysis
Per protocol analysis

Allocation concealment
No

Trial registration
None

Funding source
Non-industry funded