To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
November 2012
Kidney transplantation
Late Calcineurin Inhibitor Withdrawal Prevents Progressive Left Ventricular Diastolic Dysfunction in Renal Transplant Recipients.
Mourer JS, Ewe SH, et al. Transplantation 2012; 94(7): 721-728.
Neutralization Serotyping of BK Polyomavirus Infection in Kidney Transplant Recipients.
Pastrana DV, Brennan DC, et al. PLoS Pathogens 2012; 8(4): e1002650.
A 1-Year Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Ibandronate on Bone Loss Following Renal Transplantation.
Smerud KT, Dolgos S, et al. American Journal of Transplantation 2012 [record in progress].
A Randomized, Double-blind, Placebo-Controlled Study of Single Dose Rituximab as Induction in Renal Transplantation: a 3-year Follow-up.
Tyden G, Ekberg H, et al. Transplantation 2012; 94(3): e21-e22.
Kidney Function and Risk of Cardiovascular Disease and Mortality in Kidney Transplant Recipients: The FAVORIT Trial.
Weiner DE, Carpenter MA, et al. American Journal of Transplantation 2012; 12(9): 2437-2445.
Liver transplantation
The Influence of Pharmacological Peconditioning with Sevoflurane on Incidence of Early Allograft Dysfunction in Liver Transplant Recipients.
Minou AF, Dzyadzko AM, et al. Anesthesiology Research and Practice 2012; 930487.
Epinephrine and Phenylephrine Pretreatments for Preventing Postreperfusion Syndrome During Adult Liver Transplantation.
Ryu HG, Jung CW, et al. Liver Transplantation 2012 [record in progress].
Efficacy and Safety of Maribavir Dosed at 100 mg Orally Twice Daily for the Prevention of Cytomegalovirus Disease in Liver Transplant Recipients: A Randomized, Double-Blind, Multicenter Controlled Trial.
Winston DJ, Saliba F, et al. American Journal of Transplantation 2012 [record in progress].
Heart transplantation
Virtual Histology Assessment of Cardiac Allograft Vasculopathy Following Introduction of Everolimus-Results of a Multicenter Trial.
Arora S, Erikstad I, et al. American Journal of Transplantation 2012; 12(10):2700-2709.
Other
Perceptions of organ donation after circulatory determination of death among critical care physicians and nurses: A national survey*.
Hart JL, Kohn R, et al. Critical Care Medicine 2012; 40(9): 2595-2600.