To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
October 2013
Kidney transplantation
Treatment with everolimus is associated with a procoagulant state.
Baas MC, Gerdes VE, et al. Thrombosis Research 2013; 132 (2): 307–311
A comparative, randomized trial of concentration-controlled sirolimus combined with reduced-dose tacrolimus or standard-dose tacrolimus in renal allograft recipients.
Bechstein WO, Paczek L, et al. Transplantation Proceedings 2013; 45(6): 2133-2140.
A randomized pilot study of donor stem cell infusion in living-related kidney transplant recipients receiving alemtuzumab.
Ciancio G, Sageshima J, et al. Transplantation 2013;96(9):800-6
A comparison between two tacrolimus-based immunosuppression regimens in renal transplant recipients: 7-year follow-up.
Foroncewicz B, Mucha K, et al. Annals of Transplantation 2013; 18: 384-392.
Quinolone prophylaxis for the prevention of BK virus infection in kidney transplantation: study protocol for a randomized controlled trial.
Humar A, Gill J, et al. Trials 2013; 14: 185.
Incision length for kidney transplantation does not influence short- or long-term outcome: a prospective randomized controlled trial.
Malinka T, Banz VM, et al. Clinical Transplantation 2013; 27(5): E538-45.
Liver transplantation
Respiratory risk score for the prediction of 3-month mortality and prolonged ventilation after liver transplantation.
Kleine M, Vondran J, et al. Liver Transplantation 2013; 19(8): 862-871.
Heart transplantation
A 1-year randomized controlled study of everolimus versus mycophenolate mofetil with reduced-dose cyclosporine in maintenance heart transplant recipients.
Bara C, Dengler MA, et al Transplantation Proceedings 2013; 45(6): 2387-2392.
Various organs
Preventive intervention for living donor psychosocial outcomes: feasibility and efficacy in a randomized controlled trial.
Dew MA, Dimartini AF, et al. American Journal of Transplantation 2013; 13(10): 2672-84.
Pretransplantation GAD-autoantibody status to guide prophylactic antibody induction therapy in simultaneous pancreas and kidney transplantation
Ringers J, van der Torren CR, et al. Transplantation 2013; 96(8): 745-52