To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
March 2014
Kidney transplantation
Interstitial pneumonitis caused by everolimus: a case-cohort study in renal transplant recipients.
Baas MC, Struijk GH, et al. Transplant International 2014; 27(5): 428-436
Can a combined screening/treatment programme prevent premature failure of renal transplants due to chronic rejection in patients with HLA antibodies: study protocol for the multicentre randomised controlled OuTSMART trial.
Dorling A, Rebolla-Mesa-I, et al. Trials. 2014; 15, 30.
Effect of periodontal treatment in renal transplant recipients.
Pejcic A, Djordjevic V, et al. Medical Principals and Practice 2014; 23 149-153.
The identification of novel potential injury mechanisms and candidate biomarkers in renal allograft rejection by quantitative proteomics.
Sigdel TK, Salomonis N, et al. Molecular & Cell Proteomics 2014; 13 (2): 621-631
A randomized controlled trial comparing intravesical to extravesical ureteroneocystostomy in living donor kidney transplantation recipients.
Slagt IK, Dor FJ, et al. Kidney International 2014; 85(2): 471-477.
Efficacy of transversus abdominis plane block for acute postoperative pain relief in kidney recipients: a double-blinded clinical trial.
Soltani MS, Dabir A, et al. Pain Medicine 2014; 15(3): 460-464.
Short-term efficacy and safety of sitagliptin treatment in long-term stable renal recipients with new-onset diabetes after transplantation.
Strom Halden TA, Asberg A, et al. Nephrology Dialysis Transplantation 2014; 29(4): 926-933.
Liver transplantation
REFINE: A randomized trial comparing cyclosporine A and tacrolimus on fibrosis after liver transplantation for hepatitis C.
Levy G, Villamil FG, et al. American Journal of Transplantation 2014; 14(3): 635-646.
Lung transplantation
Effect of high-frequency chest wall oscillation versus chest physiotherapy on lung function after lung transplant: A pilot study.
Esguerra-Gonzales A, Ilagan-Honorio M, et al. Applied Nursing Research. 2013, 27, 59-66.
Other
What are effective approaches to increasing rates of organ donor registration among ethnic minority populations: a systematic review.
Deedat S, Kenten, C, et al. BMJ Open.2013; 3, e003453.