Transplant Trial Watch

To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.


May 2016

Kidney transplantation

Early Steroid Withdrawal in Recipients of a Kidney Transplant From a Living Donor: Experience of a Single Mexican Center.
Andrade-Sierra J, Rojas-Campos E, et al. Transplantation Proceedings 2016; 48(1): 42-49.

Humoral immunity after kidney transplantation: impact of two randomized immunosuppressive protocols.
Legris T, Picard C, et al. Annals of Transplantation 2013; 18: 622-634.

A Randomized Controlled Trial of a Mobile Medical App for Kidney Transplant Recipients: Effect on Use of Sun Protection.
Robinson JK, Friedewald JJ, et al Transplantation Direct 2016; 2(1).

Variability of mycophenolic acid elimination in the renal transplant recipients - population pharmacokinetic approach.
Velickovic-Radovanovic RM, Jankovic SM, et al. Renal Failure 2015; 37(4): 652-658.

Long-term Follow-up of Kidney Transplant Recipients in the Spare-the-Nephron-Trial.
Weir MR, Pearson TC, et al. Transplantation 2016; [record in progress].

Influence of the Interval Between Renal Computed Tomographic Angiography and Kidney Transplantation on Allograft Function: A Prospective, Randomized, Controlled Trial.
Xie L, Wang X, et al. Transplantation Proceedings 2015; 47(10): 2822-2826.

Liver transplantation

Do patient characteristics influence efficacy and renal outcomes in liver transplant patients receiving everolimus?
De Simone P, Saliba F, et al. Clinical Transplantation 2016; 30(3):279-88

Heart transplantation

Postexercise Hypotension after Heart Transplant: Water- versus Land-Based Exercise.
Castro RE, Guimaraes GV, et al. Medicine & Science in Sports & Exercise 2016 May; 48(5): 804-10

Various organs

Effects of Message Framing and Exemplars on Promoting Organ Donation.
Chien Y, and Chang W. Psychological Reports 2015; 117(3): 692-702.

Contribution of population pharmacokinetics to dose optimization of ganciclovir/valganciclovir in solid organ transplant patients.
Padulles A, Colom H, et al. Antimicrobial Agents & Chemotherapy 2016; 60(4):1992-2002