To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
June 2017
Kidney transplantation
Overweight Kidney Transplant Recipients Are at Risk of Being Overdosed Following Standard Bodyweight-Based Tacrolimus Starting Dose.
Andrews LM, de Winter BCM, et al. Transplantation Direct 2017; 3(2): e129.
Comparison of Pfannenstiel or Extended Iliac Port Site Kidney Extraction in Laparoscopic Donor Nephrectomy: Do We Have Consensus?
Iemsupakkul P, Kongchareonsombat W, et al. Experimental and clinical transplantation 2017; 15(2): 138-142.
Glucose-lowering agents for treating pre-existing and new-onset diabetes in kidney transplant recipients.
Lo CM, Jun M, et al. Cochrane Database of Systematic Reviews 2017; 2: CD009966.
Chlorthalidone Versus Amlodipine for Hypertension in Kidney Transplant Recipients Treated With Tacrolimus: A Randomized Crossover Trial.
Moes AD, Hesselink DA, et al. American Journal of Kidney Diseases 2017; 69(6): 796-804.
Liver transplantation
Systematic review and meta-analysis of studies of biliary reconstruction in adult living donor liver transplantation.
Chok KSH and Lo CM. ANZ Journal of Surgery 2017; 87(3): 121-125.
Double Blind Randomized Controlled Trial of the Routine Peri-operative Use of Terlipressin in Adult Living Donor Liver Transplantation.
Reddy MS, Kaliamoorthy I, et al. Liver Transplantation 2017 [record in progress].
Prevention of hypothermia in patients undergoing orthotopic liver transplantation using the humigard(R) open surgery humidification system: a prospective randomized pilot and feasibility clinical trial.
Weinberg L, Huang A, et al. BMC Surg 2017; 17(1): 10.
Heart transplantation
The Effect of Desmopressin on the Amount of Bleeding and Transfusion Requirements in Patients undergoing Heart Transplant Surgery.
Jahangirifard A, Razavi MR, et al. Basic & Clinical Pharmacology & Toxicology 2017; 22: 22.
Various organs
Two Doses of Inactivated Influenza Vaccine Improve Immune Response in Solid Organ Transplant Recipients: Results of TRANSGRIPE 1-2, a Randomized Controlled Clinical Trial.
Cordero E, Roca-Oporto C, et al. Clinical Infectious Diseases 2017; 64(7): 829-838.
Efficacy of a medication adherence enhancing intervention in transplantation: The MAESTRO-Tx trial.
Dobbels F, De Bleser L, et al. Journal of Heart & Lung Transplantation 2017; 06: 06.