To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
February 2012
Kidney transplantation
Alteration of panel-reactive antibodies following treatment with either atorvastatin or low-dose mycophenolate mofetil in sensitized hemodialysis patients.
Ghorbani A, Shahbazian H, et al. Iranian Journal of Kidney Diseases, 5(5): 342-346, 2011.
Comparison of alendronate and pamidronate on bone loss in kidney transplant patients for the first 6 months of transplantation.
Omidvar B, Ghorbani A, et al. Iranian Journal of Kidney Diseases, 5(6): 420-424, 2011.
Prophylactic effect of mycophenolate mofetil on early outcomes of living donor kidney transplantation.
Samadzadeh B, Alemi M, et al. Iranian Journal of Kidney Diseases, 6(1): 63-68, 2012.
Osteoprotegerin as a predictor of renal and cardiovascular outcomes in renal transplant recipients: follow-up data from the ALERT study.
Svensson M, Dahle DO, et al. Nephrology Dialysis Transplantation, 27(6):2571-5, 2012.
Low-grade albuminuria reduction with angiotensin II type 1 receptor blocker in renal transplant recipients.
Uchida J, Machida Y, et al. Journal of Nephrology, 24(4): 515-521, 2011.
A randomized trial with steroids and antithymocyte globulins comparing cyclosporine/Azathioprine versus tacrolimus/mycophenolate mofetil (CATM2) in renal transplantation.
Vacher-Coponat H, Moal V, et al. Transplantation 93(4):437-43, 2012.
Dietary restriction modifies certain aspects of the postoperative acute phase response.
van Ginhoven TM, Dik WA, et al. Journal of Surgical Research, 171(2): 582-589, 2011.
Liver transplantation
Impact of liver transplantation on the survival of patients treated for hepatorenal syndrome type 1.
Boyer TD, Sanyal AJ, et al. Liver Transplantation, 17(11): 1328-1332, 2011.
Results of live donor liver transplantation in patients with hepatitic C virus infection: the HCV 3 trial experience.
Sher L, Jennings L, et al. Clinical Transplantation, 26(3): 502-509, 2012.
Heart transplantation
A high-intensity exercise program improves exercise capacity, self-perceived health, anxiety and depression in heart transplant recipients: a randomized, controlled trial.
Christensen SB, Dall CH, et al. The Journal of Heart and Lung Transplantation, 31(1): 106-107, 2012.