To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
July 2012
Kidney transplantation
Management of Ureteral Complications in Renal Transplantation: Prevention and Treatment.
Asadpour A, Molaei M, et al. Saudi Journal of Kidney Diseases & Transplantation, 22(1): 72-74, 2011.
Extracorporeal Photopheresis as an Antirejection Prophylaxis in Kidney Transplant Recipients: Preliminary Results.
Kusztal M, Koscielska-Kasprzak K, et al. Transplantation Proceedings, 43(8): 2938-2940, 2011.
A Comparative Study of Impact of Infusion of Ringer's Lactate Solution versus Normal Saline on Acid-base Balance and Serum Electrolytes during Live Related Renal Transplantation.
Modi MP, Vora KS, et al. Saudi Journal of Kidney Diseases & Transplantation, 23(1): 135-137, 2012.
Randomized Trial Comparing Late Concentration-controlled Calcineurin Inhibitor or Mycophenolate Mofetil Withdrawal.
Mourer JS, Hartigh J, et al. Transplantation, 93(9): 887-894, 2012.
The "House Calls" Trial: A Randomized Controlled Trial to Reduce Racial Disparities in Live Donor Kidney Transplantation: Rationale and Design.
Rodrigue JR, Pavlakis M, et al. Contemporary Clinical Trials, 33(4):811-818, 2012.
Effect of Cinacalcet on Renal Electrolyte Handling and Systemic Arterial Blood Pressure in Kidney Transplant Patients with Persistent Hyperparathyroidism.
Zitt E, Woess E, et al. Transplantation 92: 883-889, 2011.
Liver transplantation
Treatment of Recurrent HCV Infection Following Liver Transplantation: Results of a Multicenter, Randomized, versus Placebo, Trial of Ribavirin alone as Maintenance Therapy after One Year of Peginterferon Alfa-2A plus Ribavirin.
Calmus Y, Duvoux C, et al. Journal of Hepatology, 57(3): 564-571, 2012.
Tying a Slipknot to an Intubation Stylet for Facilitating Insertion of a Nasogastric Tube in Liver Transplant Recipients: a Prospective, Randomized Study.
Tsai YF, Liu FC, et al. Transplantation Proceedings, 44(2): 438-44, 2012.
Lung transplantation
Tacrolimus and Cyclosporine Have Differential Effects on the Risk of Development of Bronchiolitis Obliterans Syndrome: Results of a Prospective, Randomized International Trial in Lung Transplantation.
Treede H, Glanville AR, et al. Journal of Heart & Lung Transplantation, 31(8):797-804, 2012.
Other
Increasing Organ Donation via Anticipated Regret (INORDAR): Protocol for a Randomised Controlled Trial.
O'Carroll RE, Ferguson E, et al. BMC Public Health, 12(1): 169, 2012.