To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
September 2012
Kidney transplantation
A Randomized Pharmacokinetic Study of Generic Tacrolimus versus Reference Tacrolimus in Kidney Transplant Recipients.
Alloway RR, Sadaka B, et al. American Journal of Transplantation 12(10): 2825-2831,2012
Mycophenolate Versus Azathioprine for Kidney Transplantation: A 15-Year Follow-Up of a Randomized Trial.
Clayton PA, McDonald SP, et al. Transplantation, 94(2):152-158, 2012.
Transversus Abdominis Plane Block for Analgesia in Renal Transplantation: A Randomized Controlled Trial.
Freir NM, Murphy C, et al. Anesthesia and Analgesia, 115(4): 953-957, 2012.
Subclinical Inflammation and Chronic Renal Allograft Injury in a Randomized Trial on Steroid Avoidance in Pediatric Kidney Transplantation.
Naesens M, Salvatierra O, et al. American Journal of Transplantation [record in progress].
Complete Steroid Avoidance Is Effective and Safe in Children With Renal Transplants: A Multicenter Randomized Trial with Three-Year Follow-Up.
Sarwal MM, Ettenger R, et al. American Journal of Transplantation, 12(10): 2719-2729. 2012.
The Effect of An Educational Intervention for Renal Recipients: A Randomized Controlled Trial.
Urstad KH, Oyen O, et al. Clinical Transplantation, 26(3): E246-253, 2012.
Liver transplantation
Protection of the Intrahepatic Biliary Tree by Contemporaneous Portal and Arterial Reperfusion: Results of A Prospective Randomized Pilot Study.
Baccarani U, Rossetto A, et al. Updates in Surgery, 64(3): 173-177, 2012.
A Randomized Multicenter Study Comparing a Tacrolimus-Based Protocol with and without Steroids in HCV-Positive Liver Allograft Recipients.
Neumann U, Samuel D, et al. Journal of transplantation, AD 894215, 2012.
Heart transplantation
Simple score to assess the risk of rejection after orthotopic heart transplantation.
Kilic AE, Weiss S, et al. Circulation 125(24): 3013-3021, 2012.
Randomized Controlled Trial of Sirolimus Conversion in Cardiac Transplant Recipients With Renal Insufficiency
Zuckermann A, Keogh A, et al. American Journal of Transplantation, 12(9): 2487-2497, 2012.