To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
January 2016
Kidney transplantation
Long-term efficacy of atorvastatin in allograft rejection following renal transplantation: A randomized clinical trial.
Amirzargar MA, Hosseini AT, et al. Saudi Journal of Kidney Diseases & Transplantation 2015; 26(5): 953-957.
Enteric-coated mycophenolate sodium given in combination with tacrolimus has a lower incidence of serious infections in Asian renal-transplant recipients compared with mycophenolate mofetil.
Feng JJ, Zhang LW, et al. International Journal of Clinical Practice 2015; Supplement (183): 1-7.
Recipient obesity and outcomes after kidney transplantation: a systematic review and meta-analysis.
Hill CJ, Courtney AE, et al. Nephrology Dialysis Transplantation 2015; 30(8): 1403-1411.
No relevant pharmacokinetic interaction between pantoprazole and mycophenolate in renal transplant patients: a randomized crossover study.
Rissling O, Glander P, et al. British Journal of Clinical Pharmacology 2015; 80(5): 1086-1096.
Caudal extradural catheterization in pediatric renal transplant and its effect on perioperative hemodynamics and pain scoring: a prospective randomized study.
Soaida SM, ElSheemy MS, et al. J Anesth 2015 [record in progress].
A Randomized 2x2 Factorial Clinical Trial of Renal Transplantation: Steroid-Free Maintenance Immunosuppression with Calcineurin Inhibitor Withdrawal after Six Months Associates with Improved Renal Function and Reduced Chronic Histopathology.
Stevens RB, Foster KW, et al. PLoS ONE 2015 [Electronic Resource] 10(10): e0139247.
Liver transplantation
Effect of a physical exercise program on the functional capacity of liver transplant patients.
Garcia AMC, Veneroso CE, et al. Transplantation Proceedings 2014; 46(6): 1807-1808.
Lung transplantation
A novel risk score that incorporates recipient and donor variables to predict 1-year mortality in the current era of lung transplantation.
Grimm JC, Valero V, et al. Journal of Heart & Lung Transplantation 2015; 34(11): 1449-1454.
Various organs
Coping-Infused Dialogue through Patient-Preferred Live Music: A Medical Music Therapy Protocol and Randomized Pilot Study for Hospitalized Organ Transplant Patients.
Hogan TJ, and Silverman MJ. J Music Ther 2015 [record in progress].
You've got mail! An examination of a statewide direct-mail marketing campaign to promote deceased organ donor registrations.
Quick BL, LaVoie NR, et al. Clinical Transplantation 2015; 29(11): 997-1003.