To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
June 2012
Kidney transplantation
Randomized Trial of Short-Course High-Dose Erythropoietin in Donation after Cardiac Death Kidney Transplant Recipients.
Aydin Z, Mallat MJ, et al. American Journal of Transplantation, 12(7):1793-1800, 2012.
Cyclosporin but not Everolimus Inhibits Chemokine Receptor Expression on CD4(+) T Cell Subsets Circulating in the Peripheral Blood of Renal Transplant Recipients.
Hoerning A, Kohler S, et al. Clinical & Experimental Immunology, 168(2): 251-259, 2012.
Everolimus Plus Early Tacrolimus Minimization: a Phase III, Randomized, Open-label, Multicentre Trial in Renal Transplantation.
Langer RM, Hene R, et al. Transplant International, 25(5): 592-602, 2012.
Five-Year Results of a Randomized Trial Comparing De Novo Sirolimus and Cyclosporine in Renal Transplantation: The Spiesser Study.
Lebranchu Y, Snanoudj R, et al. American Journal of Transplantation, 12(7):1801-1810, 2012.
Impact of Early Ureteric Stent Removal and Cost-benefit Analysis in Kidney Transplant Recipients: Results of a Randomized Controlled Study.
Parapiboon W, Ingsathit A, et al. Transplantation Proceedings, 44(3): 737-739, 2012.
High Incidence of Bacteriuria in Early Post-kidney Transplantation; Results from a Randomized Controlled Study.
Parapiboon W, Ingsathit A, et al. Transplantation Proceedings, 44(3): 734-736, 2012.
Comparative Pharmacokinetic Study of Two Mycophenolate Mofetil Formulations in Stable Kidney Transplant Recipients.
Sunder-Plassmann G, Reinke P, et al. Transplant International, 25(6): 680-686, 2012.
Induction Therapy with Autologous Mesenchymal Stem Cells in Living-related Kidney Transplants: A Randomized Controlled Trial.
Tan J, Wu W, et al. JAMA, 307(11): 1169-1177, 2012.
Liver transplantation
A Randomized, Controlled Study to Assess the Conversion from Calcineurin-Inhibitors to Everolimus after Liver Transplantation-PROTECT.
Fischer L, Klempnauer J, et al. American Journal of Transplantation, 12(7):1855-1865, 2012.
Perioperative Assessment of Terlipressin Infusion during Living Donor Liver Transplantation.
Hong SH, Lee JM, et al. Journal of International Medical Research, 40(1): 225-236, 2012.
Comparison of harmonic scalpel versus conventional knot tying for transection of short hepatic veins at liver transplantation: prospective randomized study.
Olmez A, Karabulut K, et al. Transplantation Proceedings 2012; 44(6): 1717-1719.